LY 231617
Modify Date: 2024-01-24 09:05:10
LY 231617 structure
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Common Name | LY 231617 | ||
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| CAS Number | 141545-89-3 | Molecular Weight | 299.87900 | |
| Density | N/A | Boiling Point | 316.4ºC at 760 mmHg | |
| Molecular Formula | C17H30ClNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 14.3ºC | |
Use of LY 231617LY231617 is a potent and blood-brain barrier penetrable antioxidant. LY231617 is a neuroprotective agent in brain, it can be used for the research of nervous disease[1][2]. |
| Name | 2,6-ditert-butyl-4-(ethylaminomethyl)phenol,hydrochloride |
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| Description | LY231617 is a potent and blood-brain barrier penetrable antioxidant. LY231617 is a neuroprotective agent in brain, it can be used for the research of nervous disease[1][2]. |
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| Related Catalog | |
| In Vitro | LY231617 (0.25, 1, 5, 10, and 25 μM; overnight) attenuates H2O2 toxicity to hippocampal cultures and shows the best effect at a concertration of 10 μM[1]. LY231617 (5 μM; overnight) attenuates 8-isoprostane production and glutathione depletion[1]. |
| In Vivo | LY231617 (50 mg/kg; p.o. 30 minutes before occlusion) reduces global ischemic neuronal injury in rats[2]. LY231617 (20 mg/kg; i.v. 30 minutes after occlusion) protects hippocampus and striatum from four-vessel occlusion[2]. Animal Model: Male Wistar rats four-vessel occlusion[2] Dosage: 50 mg/kg Administration: Oral gavage; 50 mg/kg 30 minutes before occlusion Result: Significantly protected both the hippocampus and striatum from 30 minutes of four-vessel occlusion. Animal Model: Male Wistar rats four-vessel occlusion[2] Dosage: 20 mg/kg Administration: Intravenous injection ; 20 mg/kg 30 minutes after occlusion Result: Significantly protected the hippocampus and the striatum when given 30 minutes after the onset of the ischemia at the time of reperfusion. |
| Boiling Point | 316.4ºC at 760 mmHg |
|---|---|
| Molecular Formula | C17H30ClNO |
| Molecular Weight | 299.87900 |
| Flash Point | 14.3ºC |
| Exact Mass | 299.20200 |
| PSA | 32.26000 |
| LogP | 5.28960 |
| Vapour Pressure | 0.000222mmHg at 25°C |
| Index of Refraction | 1.503 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: LY 231617
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Ly-231617
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: LY 231617
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1600/5 mg
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