AMG-333

Modify Date: 2024-02-02 11:41:10

AMG-333 structure	Common Name	AMG-333
	CAS Number	1416799-28-4	Molecular Weight	453.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₂F₅N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AMG-333

AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.

Name	AMG 333
Synonym	More Synonyms

Description	AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
Target	IC50: 13 nM (TRPM8)[1]
References	[1]. Horne DB, et al. Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine. J Med Chem. 2018 Sep 27;61(18):8186-8201.

Molecular Formula	C₂₀H₁₂F₅N₃O₄
Molecular Weight	453.32

Hazard Codes	Xi

MFCD31813692

DC Chemicals Limited
China
Product Name: AMG-333
Price: $800.0/100mg $1400.0/250mg $2800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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