AMG-076

Modify Date: 2025-08-28 09:36:44

AMG-076 Structure
AMG-076 structure
Common Name AMG-076
CAS Number 693823-79-9 Molecular Weight 462.54800
Density N/A Boiling Point N/A
Molecular Formula C26H33F3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AMG-076


AMG-076 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) with binding IC50 of 0.6 nM, with dramatically reduced hERG liability (IC50>5 uM).

 Names

Name 1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C26H33F3N2O2
Molecular Weight 462.54800
Exact Mass 462.24900
PSA 56.33000
LogP 6.14750

 Synonyms

UNII-HX4T7JEV3D
AMG-076 free base
AMG 076
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