Fenclonine

Modify Date: 2024-01-08 18:13:52

Fenclonine Structure
Fenclonine structure
Common Name Fenclonine
CAS Number 14173-39-8 Molecular Weight 199.634
Density 1.3±0.1 g/cm3 Boiling Point 339.5±32.0 °C at 760 mmHg
Molecular Formula C9H10ClNO2 Melting Point 235-238ºC
MSDS Chinese USA Flash Point 159.1±25.1 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of Fenclonine


4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2)[1].

 Names

Name 4-Chloro-Phe-OH
Synonym More Synonyms

 Fenclonine Biological Activity

Description 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2)[1].
Related Catalog
References

[1]. Chasen J Greig, et al. Enhanced serotonin signaling increases intestinal neuroplasticity. J Surg Res. 2016 Nov;206(1):151-158.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 339.5±32.0 °C at 760 mmHg
Melting Point 235-238ºC
Molecular Formula C9H10ClNO2
Molecular Weight 199.634
Flash Point 159.1±25.1 °C
Exact Mass 199.040009
PSA 63.32000
LogP 1.71
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.590

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H317
Precautionary Statements P280-P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;
Risk Phrases R25;R43
Safety Phrases S36/37-S45
RIDADR UN 2811
WGK Germany 3
Hazard Class 6.1
HS Code 2922499990

 Synthetic Route

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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 Synonyms

Dl-4-Chlorophenylalanine
L-4-Chlorophenylalanine
para-Chlorophenylalanine
PCPA
(±)-p-Chlorophenylalanine
(S)-2-Amino-3-(4-chlorophenyl)propanoic acid
p-Cl-L-Phe-OH
p-Chloro-L-phenylalanine
p-Chloro-DL-phenylalanine
4-Chlorophenylalanine
4-Chloro-phenylalanine
Phenylalanine, 4-chloro-
4-Chloro-3-phenylalanine
DL-p-Chlorophenylalanine
4-Chloro-DL-phenylalanine
p-Chlorophenylalanine
4-Chloro-L-phenylalanine
MFCD00063065
p-CPA
3-(p-chlorophenyl)-DL-alanine
Fenclonine
(2S)-2-amino-3-(4-chlorophenyl)propanoic acid
DL-3-(p-Chlorophenyl)alanine
EINECS 238-023-5
(S)-4-Chlorophenylalanine
(±)-p-Chlorphenylalanine
L-p-Chlorophenylalanine
4-Chloro-dl-β-phenylalanine
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