Iminodiacetic acid

Modify Date: 2024-01-02 15:23:45

Iminodiacetic acid Structure
Iminodiacetic acid structure
Common Name Iminodiacetic acid
CAS Number 142-73-4 Molecular Weight 133.10
Density 1.4±0.1 g/cm3 Boiling Point 370.6±27.0 °C at 760 mmHg
Molecular Formula C4H7NO4 Melting Point 243 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 177.9±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Iminodiacetic acid


Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals[1]. Iminodiacetic acid can be used for removal of toxic metal ions from water[2]. Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome)[3].

 Names

Name iminodiacetic acid
Synonym More Synonyms

 Iminodiacetic acid Biological Activity

Description Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals[1]. Iminodiacetic acid can be used for removal of toxic metal ions from water[2]. Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome)[3].
Related Catalog
References

[1]. M D Loberg, et al. Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid. J Nucl Med. 1976 Jul;17(7):633-8.

[2]. Misra RK, et al. Iminodiacetic acid functionalized cation exchange resin for adsorptive removal of Cr(VI), Cd(II), Ni(II) and Pb(II) from their aqueous solutions. J Hazard Mater. 2011 Jan 30;185(2-3):1508-12.

[3]. Shihui Lin, et al. Explore potential plasma biomarkers of acute respiratory distress syndrome (ARDS) using GC-MS metabolomics analysis. Clin Biochem. 2019 Apr;66:49-56.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 370.6±27.0 °C at 760 mmHg
Melting Point 243 °C (dec.)(lit.)
Molecular Formula C4H7NO4
Molecular Weight 133.10
Flash Point 177.9±23.7 °C
Exact Mass 133.037506
PSA 86.63000
LogP -1.40
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.501
Water Solubility 2.43 g/100 mL (5 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AI2975000
CHEMICAL NAME :
Acetic acid, iminodi-
CAS REGISTRY NUMBER :
142-73-4
BEILSTEIN REFERENCE NO. :
0878499
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H7-N-O4
MOLECULAR WEIGHT :
133.12
WISWESSER LINE NOTATION :
QV1M1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4728 No. of Facilities: 25 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 293 (estimated) No. of Female Employees: 43 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS AI2975000
HS Code 29224995

 Synthetic Route

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles36

More Articles
Selective Solid-Phase Extraction of Zinc(II) from Environmental Water Samples Using Ion Imprinted Activated Carbon.

J. AOAC Int. 98(1) , 206-12, (2015)

A simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon with iminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. T...

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

J. Med. Chem. 51 , 6740-51, (2008)

The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared ...

Immobilized metal affinity chromatography using open tubular capillary for phosphoprotein analysis: comparison between polymer brush coating and surface functionalization.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(27) , 2852-9, (2011)

In the present article, open tubular-IMAC columns, functionalized by iminodiacetic acid (IDA) for the immobilization of Fe(3+), were prepared by in situ chemical modification of fused silica capillary...

 Synonyms

2-(carboxymethylamino)acetic acid
Iminodiacetic acid
N-(carboxymethyl)- glycine
MFCD00004280
diglycine
IDA
EINECS 205-555-4
Glycine, N-(carboxymethyl)-
2,2'-Azanediyldiacetic acid
2,2'-Iminodiacetic acid
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