tert-Butyl (6-bromohexyl)carbamate
tert-Butyl (6-bromohexyl)carbamate structure
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Common Name | tert-Butyl (6-bromohexyl)carbamate | ||
|---|---|---|---|---|
| CAS Number | 142356-33-0 | Molecular Weight | 280.202 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 340.1±25.0 °C at 760 mmHg | |
| Molecular Formula | C11H22BrNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 159.5±23.2 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
Use of tert-Butyl (6-bromohexyl)carbamateBoc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. |
| Name | tert-Butyl (6-bromohexyl)carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Jan Anderl, et al. Amatoxin-antibody conjugates. WO2016142049A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 340.1±25.0 °C at 760 mmHg |
| Molecular Formula | C11H22BrNO2 |
| Molecular Weight | 280.202 |
| Flash Point | 159.5±23.2 °C |
| Exact Mass | 279.083374 |
| PSA | 38.33000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.473 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R41 |
| Safety Phrases | 26-39 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 3 |
| HS Code | 2924199090 |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Keller; Haner Helvetica Chimica Acta, 1993 , vol. 76, # 2 p. 884 - 892 |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: US6878715 B1, ; |
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Detail
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| Literature: US2002/28823 A1, ; |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 37, # 16 p. 2537 - 2551 |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4208 - 4212 |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
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tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
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~%
tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
|
~%
tert-Butyl (6-b... CAS#:142356-33-0 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4208 - 4212 |
| Precursor 9 | |
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| DownStream 1 | |
CAS#:1938-58-5| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine nanoparticles for potential hypoxia-responsive delivery of doxorubicin.
J. Biomater. Sci. Polym. Ed. 27 , 40-54, (2015) Tumor microenvironment-responsive nano drug delivery vehicles are gaining mounting attention in the field of biomedical sciences. The hypoxic response of the tumorous cells due to very low partial pre... |
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T.H. Keller, R. Haener
Helv. Chim. Acta 76 , 884, (1993)
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D. Damour et al.
Bioorg. Med. Chem. Lett. 6 , 1667 , (1996)
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| tert-butyl N-(6-bromohexyl)carbamate |
| 2-Methyl-2-propanyl (6-bromohexyl)carbamate |
| tert-Butyl (6-bromohexyl)carbamate |
| Carbamic acid, N-(6-bromohexyl)-, 1,1-dimethylethyl ester |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: tert-Butyl (6-bromohexyl)carbamate
- Price: ￥Inquiry/1mg
- Purity: 97.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-Boc-6-Bromohexylamin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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