Gluten Exorphin C

Modify Date: 2024-01-02 23:29:58

Gluten Exorphin C Structure
Gluten Exorphin C structure
Common Name Gluten Exorphin C
CAS Number 142479-62-7 Molecular Weight 591.69600
Density N/A Boiling Point N/A
Molecular Formula C29H45N5O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gluten Exorphin C


Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

 Names

Name h-ypisl-oh
Synonym More Synonyms

 Gluten Exorphin C Biological Activity

Description Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.
Related Catalog
Target

IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)[1]

In Vitro Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity[1].
References

[1]. Fukudome S, et al. Gluten exorphin C. A novel opioid peptide derived from wheat gluten. FEBS Lett. 1993 Jan 18;316(1):17-9.

 Chemical & Physical Properties

Molecular Formula C29H45N5O8
Molecular Weight 591.69600
Exact Mass 591.32700
PSA 211.39000
LogP 1.68740
Storage condition 2-8℃

 Synonyms

EXORPHIN C TRIFLUOROACETATE SALT
Gluten Exorphin C