Mal-amido-PEG2-TFP ester
Modify Date: 2024-01-14 21:14:06
Mal-amido-PEG2-TFP ester structure
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Common Name | Mal-amido-PEG2-TFP ester | ||
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| CAS Number | 1431291-44-9 | Molecular Weight | 476.376 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 640.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H20F4N2O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 340.9±31.5 °C | |
Use of Mal-amido-PEG2-TFP esterMal-amido-PEG2-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2,3,5,6-Tetrafluorophenyl 3-[2-(2-{[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]propanoate |
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| Synonym | More Synonyms |
| Description | Mal-amido-PEG2-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 640.1±55.0 °C at 760 mmHg |
| Molecular Formula | C20H20F4N2O7 |
| Molecular Weight | 476.376 |
| Flash Point | 340.9±31.5 °C |
| Exact Mass | 476.120667 |
| LogP | 1.11 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.516 |
| 2,3,5,6-Tetrafluorophenyl 3-[2-(2-{[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]propanoate |
| Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,3,5,6-tetrafluorophenyl ester |