GX 201
Modify Date: 2024-01-19 09:06:42
GX 201 structure
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Common Name | GX 201 | ||
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| CAS Number | 1788071-27-1 | Molecular Weight | 563.00 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H27ClF4N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GX 201GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7[1]. |
| Name | GX-201 |
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| Description | GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7[1]. |
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| Related Catalog | |
| In Vivo | GX-201 has a relatively long half-life in mice[1]. GX-201 produces analgesia at a free plasma concentration about 3 times the IC50 for high-affinity channel block[1]. GX-201 inhibits nociceptive responses induced by formalin and inflammatory pain caused by complete Freund’s adjuvant (CFA)[1]. Animal Model: Wild-Type Mice[1]. Dosage: 0.3, 1, 3 mg/kg. Administration: Orally, once. Result: Produced a dose-dependent inhibition of the nociceptive events. |
| References |
| Molecular Formula | C25H27ClF4N2O4S |
|---|---|
| Molecular Weight | 563.00 |