AGI-12026

Modify Date: 2024-01-17 19:28:38

AGI-12026 Structure
AGI-12026 structure
Common Name AGI-12026
CAS Number 1446501-77-4 Molecular Weight 443.35
Density N/A Boiling Point N/A
Molecular Formula C18H15F6N7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AGI-12026


AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma[1].

 Names

Name AGI-12026

 AGI-12026 Biological Activity

Description AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma[1].
Related Catalog
References

[1]. Konteatis Z, et al. Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma. ACS Med Chem Lett. 2020;11(2):101-107.

 Chemical & Physical Properties

Molecular Formula C18H15F6N7
Molecular Weight 443.35
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: AGI-12026
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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