AG-120
Modify Date: 2024-01-02 08:42:07
AG-120 structure
|
Common Name | AG-120 | ||
|---|---|---|---|---|
| CAS Number | 1448347-49-6 | Molecular Weight | 582.961 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 854.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C28H22ClF3N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 470.4±34.3 °C | |
Use of AG-120Ivosidenib (AG-120) is a mutant isocitrate dehydrogenase 1 (IDH1) inhibitor with an IC50 of 12 nM for mouse IDH1R132H. |
| Name | Ivosidenib |
|---|---|
| Synonym | More Synonyms |
| Description | Ivosidenib (AG-120) is a mutant isocitrate dehydrogenase 1 (IDH1) inhibitor with an IC50 of 12 nM for mouse IDH1R132H. |
|---|---|
| Related Catalog | |
| Target |
12 nM (mouse IDH1R132H)[1] |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 854.3±65.0 °C at 760 mmHg |
| Molecular Formula | C28H22ClF3N6O3 |
| Molecular Weight | 582.961 |
| Flash Point | 470.4±34.3 °C |
| Exact Mass | 582.139404 |
| LogP | 0.38 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.651 |
| Storage condition | -20℃ |
| AG-120 |
| 2-Pyrrolidinecarboxamide, N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxo-, (2S)- |
| ivosidenib |
| N-{(1S)-1-(2-Chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxo-L-prolinamide |
| UNII:Q2PCN8MAM6 |
| (2S)-1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide |