Dexmedetomidine hydrochloride
Modify Date: 2024-01-02 18:05:01
Dexmedetomidine hydrochloride structure
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Common Name | Dexmedetomidine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 145108-58-3 | Molecular Weight | 236.740 | |
| Density | N/A | Boiling Point | 381.9ºC at 760 mmHg | |
| Molecular Formula | C13H17ClN2 | Melting Point | 153 - 158ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Dexmedetomidine hydrochlorideDexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.Target: Adrenergic alpha-2 ReceptorDexmedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Dexmedetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Dexmedetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3]. |
| Name | dexmedetomidine hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.Target: Adrenergic alpha-2 ReceptorDexmedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Dexmedetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Dexmedetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3]. |
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| Related Catalog | |
| References |
| Boiling Point | 381.9ºC at 760 mmHg |
|---|---|
| Melting Point | 153 - 158ºC |
| Molecular Formula | C13H17ClN2 |
| Molecular Weight | 236.740 |
| Exact Mass | 236.108032 |
| PSA | 28.68000 |
| LogP | 3.98030 |
| Vapour Pressure | 1.08E-05mmHg at 25°C |
| Storage condition | Desiccate at RT |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Phrases | 22-36/37/38 |
| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| RTECS | NI5156750 |
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| Dexmedetomidine (hydrochloride) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
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- Product Name: Dexmedetomidine hydrochloride
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- Purity: 99.0%
- Stocking Period: Inquiry
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