mPGES1-IN-17d

Modify Date: 2024-01-05 19:13:30

mPGES1-IN-17d structure	Common Name	mPGES1-IN-17d
	CAS Number	1469976-70-2	Molecular Weight	538.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₁₆ClF₅N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of mPGES1-IN-17d

mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM)[1].

Name	mPGES1-IN-3

Description	mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> PGE synthase
Target	IC50: 8 nM (mPGES-1)[1]
References	[1]. Muthukaman N, et al. Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5977-5984.

Molecular Formula	C₂₄H₁₆ClF₅N₄O₃
Molecular Weight	538.85

DC Chemicals Limited
China
Product Name: mPGES1-IN-17d
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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