mPGES1-IN-16
Modify Date: 2024-09-17 16:19:18
mPGES1-IN-16 structure
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Common Name | mPGES1-IN-16 | ||
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| CAS Number | 1915003-93-8 | Molecular Weight | 485.628 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H35N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of mPGES1-IN-16mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM; displays no activity against a panel of 35 receptors, ion channels, and hERG; shows IC50/IC80 of 6 nM/24 nM for inhibition of PGE2 formation in vitro in LPS-stimulated human whole blood (HWB); orally bioavailable in vivo. |
| Name | mPGES1-IN-16 |
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| Description | mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM; displays no activity against a panel of 35 receptors, ion channels, and hERG; shows IC50/IC80 of 6 nM/24 nM for inhibition of PGE2 formation in vitro in LPS-stimulated human whole blood (HWB); orally bioavailable in vivo. |
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| References | References 1. Partridge KM, et al. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1478-1483. View Related Products by Target PGE synthase |
| Molecular Formula | C30H35N3O3 |
|---|---|
| Molecular Weight | 485.628 |