Ranirestat

Modify Date: 2024-01-02 21:20:26

Ranirestat Structure
Ranirestat structure
Common Name Ranirestat
CAS Number 147254-64-6 Molecular Weight 420.18900
Density 1.83g/cm3 Boiling Point 702.7ºC at 760mmHg
Molecular Formula C17H11BrFN3O4 Melting Point N/A
MSDS Chinese USA Flash Point 378.8ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Ranirestat


Ranirestat (AS-3201) is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.

 Names

Name (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5-tetrone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.83g/cm3
Boiling Point 702.7ºC at 760mmHg
Molecular Formula C17H11BrFN3O4
Molecular Weight 420.18900
Flash Point 378.8ºC
Exact Mass 418.99200
PSA 91.97000
LogP 1.52790
Vapour Pressure 1.36E-19mmHg at 25°C
Index of Refraction 1.749
Storage condition 2-8℃

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313
RIDADR NONH for all modes of transport
RTECS WH1441246

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(3R)-2'-(4-bromo-2-fluorobenzyl)spiro[pyrrolidin-3,4'(1'H)-pyrrolo[1,2-a]pyrazin]-1',2,3',5(2'H)-tetraone
Ranirestat
Ranirestat (JAN/INN)
(R)-2-(4-bromo-2-fluorobenzyl)spiro[1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4,3'-pyrrolidine]-1,2',3,5'-tetrone
R-(-)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydro[1,2-a]pyrrolopyridine-4-spiro-3'-pyrrolidine-1,2',3'5'-tetraone
SX-3202
(3R)-2'-(4-bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'(1'H)-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2H')-tetraone
AS-3201
SX 3030