Endotoxin Inhibitor

Modify Date: 2024-01-12 18:53:04

Endotoxin Inhibitor Structure
Endotoxin Inhibitor structure
Common Name Endotoxin Inhibitor
CAS Number 147396-10-9 Molecular Weight 1224.58000
Density N/A Boiling Point N/A
Molecular Formula C55H97N15O12S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Endotoxin Inhibitor


Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1].

 Names

Name h-lys-thr-lys-cys-lys-phe-leu-lys-lys-cys-oh
Synonym More Synonyms

 Endotoxin Inhibitor Biological Activity

Description Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1].
Related Catalog
In Vivo Endotoxin inhibitor (i.p., 0.5 mg/kg) 可以显著减弱热暴露引起的 IL-1β、COX-2、IκB-β 和 LPS 活性的 mRNA 增加,以及在老年大鼠中热暴露引起的低体温和血浆 ACTH 和儿茶酚胺反应作用[1]。
References

[1]. Toshihiko Katafuchi, et al. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):24-32.  

 Chemical & Physical Properties

Molecular Formula C55H97N15O12S2
Molecular Weight 1224.58000
Exact Mass 1223.69000
PSA 526.15000
LogP 4.81840

 Synonyms

k-t-k-c-k-f-l-k-k-c
lys-thr-lys-cys-lys-phe-leu-lys-lys-cys
endotoxin inhibitor
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