Ac-Leu-Val-Lys-aldehyde

Modify Date: 2024-01-05 13:04:14

Ac-Leu-Val-Lys-aldehyde structure	Common Name	Ac-Leu-Val-Lys-aldehyde
	CAS Number	147600-40-6	Molecular Weight	384.51
	Density	1.1±0.1 g/cm3	Boiling Point	665.5±55.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₃₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	356.3±31.5 °C

Use of Ac-Leu-Val-Lys-aldehyde

Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC50s of 4 nM. Ac-Leu-Val-Lys-Aldehyde significantly reduces quinolinic acid (HY-100807)-induced striatal cell death and causes accumulation of LC3-II[1].

Name	Ac-Leu-Val-Lys-aldehyde
Synonym	More Synonyms

Description	Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC50s of 4 nM. Ac-Leu-Val-Lys-Aldehyde significantly reduces quinolinic acid (HY-100807)-induced striatal cell death and causes accumulation of LC3-II[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cathepsin B:4 nM (IC50)
References	[1]. McConnell RM, et al. Inhibition studies of some serine and thiol proteinases by new leupeptin analogues. J Med Chem. 1993 Apr 16;36(8):1084-9. [2]. Wang YR, et al. Cathepsin L plays a role in quinolinic acid-induced NF-Κb activation and excitotoxicity in rat striatal neurons. PLoS One. 2013 Sep 20;8(9):e75702.

Density	1.1±0.1 g/cm3
Boiling Point	665.5±55.0 °C at 760 mmHg
Molecular Formula	C₁₉H₃₆N₄O₄
Molecular Weight	384.51
Flash Point	356.3±31.5 °C
Exact Mass	384.273651
PSA	130.39000
LogP	0.88
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.488

cathepsin b inhibitor ii

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ac-leu-val-l-lysinal

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: AC-LEU-VAL-LYS-ALDEHYDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Ac-Leu-Val-Lys-aldehyde
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

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