3-O-Methylquercetin

Modify Date: 2025-08-25 00:38:19

3-O-Methylquercetin Structure
3-O-Methylquercetin structure
 Common Name 3-O-Methylquercetin
CAS Number 1486-70-0 Molecular Weight 316.262
Density 1.7±0.1 g/cm3 Boiling Point 643.0±55.0 °C at 760 mmHg
Molecular Formula C16H12O7 Melting Point N/A
MSDS USA Flash Point 244.7±25.0 °C
Symbol GHS06
GHS06		 Signal Word Danger

 Use of 3-O-Methylquercetin


3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1].

 Names

Name 3',4',5,7-tetrahydroxy-3-methoxyflavone
Synonym More Synonyms

 3-O-Methylquercetin Biological Activity

Description 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1].
Related Catalog
References

[1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 643.0±55.0 °C at 760 mmHg
Molecular Formula C16H12O7
Molecular Weight 316.262
Flash Point 244.7±25.0 °C
Exact Mass 316.058289
PSA 120.36000
LogP 2.02
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.762

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Hazard Codes T
Risk Phrases 25
Safety Phrases 45
RIDADR UN 2811 6.1 / PGIII
HS Code 2914509090

 Synthetic Route

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles8

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J. Nat. Prod. 52(3) , 629-33, (1989)

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 Synonyms

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxychromen-4-one
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one
3-methoxy-5,7,3',4'-tetrahydroxy-flavone
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one
3-O-Methylquercetin
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-
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