RS 23597-190
Modify Date: 2025-08-26 16:08:09
RS 23597-190 structure
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Common Name | RS 23597-190 | ||
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| CAS Number | 149719-06-2 | Molecular Weight | 363.27900 | |
| Density | N/A | Boiling Point | 486.5ºC at 760 mmHg | |
| Molecular Formula | C16H24Cl2N2O3 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | 248ºC | |
Use of RS 23597-190RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits 5-HT-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2]. |
| Name | 3-piperidin-1-ylpropyl 4-amino-5-chloro-2-methoxybenzoate,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits 5-HT-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2]. |
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| Related Catalog | |
| Target |
5-HT4 Receptor |
| In Vitro | RS 23597-190 (10 µM; 4 days) 在高葡萄糖 (30 mM)条件下显着抑制661W 细胞中超氧化物的产生[2]。 |
| In Vivo | RS 23597-190 (6.0 mg/kg；静脉注射) 抑制微型猪中 5-HT 诱导的心动过速[1]. Animal Model: Bilaterally vagotomized micropig[1] Dosage: 6.0 mg/kg Administration: I.v. Result: Antagonized 5-HT-induced tachycardia with a half-life of 77 (63-99) min. |
| References |
| Boiling Point | 486.5ºC at 760 mmHg |
|---|---|
| Molecular Formula | C16H24Cl2N2O3 |
| Molecular Weight | 363.27900 |
| Flash Point | 248ºC |
| Exact Mass | 362.11600 |
| PSA | 64.79000 |
| LogP | 4.28470 |
| Vapour Pressure | 1.29E-09mmHg at 25°C |
| Hazard Codes | Xn |
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| HS Code | 2933399090 |
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Trequinsin hydrochloride |