Biotin-C4-amide-C5-NH2

Modify Date: 2024-01-10 18:17:35

Biotin-C4-amide-C5-NH2 Structure
Biotin-C4-amide-C5-NH2 structure
Common Name Biotin-C4-amide-C5-NH2
CAS Number 151294-96-1 Molecular Weight 314.447
Density 1.1±0.0 g/cm3 Boiling Point 650.1±0.0 °C at 760 mmHg
Molecular Formula C14H26N4O2S Melting Point N/A
MSDS N/A Flash Point 347.0±0.0 °C

 Use of Biotin-C4-amide-C5-NH2


Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name N-(4-Aminobutyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Synonym More Synonyms

 Biotin-C4-amide-C5-NH2 Biological Activity

Description Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.1±0.0 g/cm3
Boiling Point 650.1±0.0 °C at 760 mmHg
Molecular Formula C14H26N4O2S
Molecular Weight 314.447
Flash Point 347.0±0.0 °C
Exact Mass 314.177643
LogP 0.37
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.533

 Synonyms

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(4-aminobutyl)hexahydro-2-oxo-
N-(4-Aminobutyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Biotin-C4-amide-C5-NH2
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