Echistatin
Echistatin structure
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Common Name | Echistatin | ||
|---|---|---|---|---|
| CAS Number | 154303-05-6 | Molecular Weight | 5417.0 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C217H341N71O74S9 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of EchistatinEchistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. |
| Name | Echistatin, α1 isoforM |
|---|
| Description | Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. |
|---|---|
| Related Catalog | |
| Target |
αvβ3 α5β1 αIIbβ3 |
| References |
| Molecular Formula | C217H341N71O74S9 |
|---|---|
| Molecular Weight | 5417.0 |
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
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Biochemical characterization of the binding of echistatin to integrin alphavbeta3 receptor.
J. Pharmacol. Exp. Ther. 283(2) , 843-53, (1997) Echistatin is a 49-amino-acid peptide belonging to the family of disintegrins that are derived from snake venoms and are potent inhibitors of platelet aggregation and cell adhesion. Integrin alphavbet... |
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Vitronectin receptor (alpha(v)beta3) mediates platelet adhesion to the luminal aspect of endothelial cells: implications for reperfusion in acute myocardial infarction.
Circulation 96(6) , 1809-18, (1997) Platelet interaction with endothelium plays an important role in the pathophysiology of coronary microcirculation. We assessed the role of the vitronectin receptor (integrin alpha(v)beta3) in platelet... |
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Structural analysis of a biologically active echistatin analogue des(46-49)-[Ala8,37]-echistatin gamma with three disulfide bonds by 2D-NMR and computer graphics.
Biochem. Biophys. Res. Commun. 220(2) , 246-54, (1996) An echistatin analogue, designated as des(46-49)-[Ala8,37]-echistatin gamma, was synthesized chemically by solid-phase peptide synthesis. The analogue was made by replacing Cys8 and Cys37 residues wit... |
- DC Chemicals Limited
- China
- Product Name: Echistatin
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: ECHISTATIN
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Echistatin
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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