CCK-B Receptor Antagonist 2
Modify Date: 2025-08-25 12:34:40
CCK-B Receptor Antagonist 2 structure
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Common Name | CCK-B Receptor Antagonist 2 | ||
|---|---|---|---|---|
| CAS Number | 155412-88-7 | Molecular Weight | 484.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CCK-B Receptor Antagonist 2CCK-B Receptor Antagonist 2, compound 15b, is a potent and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.43 nM. CCK-B Receptor Antagonist 2 also inhibits gastrin/CCK-A activity with an IC50 of 1.82 μM[1]. |
| Name | CCK-B Receptor Antagonist 2 |
|---|
| Description | CCK-B Receptor Antagonist 2, compound 15b, is a potent and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.43 nM. CCK-B Receptor Antagonist 2 also inhibits gastrin/CCK-A activity with an IC50 of 1.82 μM[1]. |
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| Related Catalog | |
| Target |
IC50: 0.43 nM (Gastrin/CCK-B); 1.82 μM (Gastrin/CCK-A)[1] |
| In Vivo | CCK-B Receptor Antagonist 2 (0.1 μmol/kg; intravenous injection) has an inhibition effect on pentagastrin-induced gastric acid secretion in anethsetized rats with an ED50 of 8.3 nmol/kg[1]. |
| References |
| Molecular Formula | C27H28N6O3 |
|---|---|
| Molecular Weight | 484.55 |
| InChIKey | ABJHMASUFPDZRW-DEOSSOPVSA-N |
| SMILES | CC(C)(C)C(=O)CN1C(=O)C(NC(=O)Nc2cccc(N)c2)N=C(c2ccccn2)c2ccccc21 |