Iodoacetamide-PEG3-azide

Modify Date: 2024-01-10 22:26:41

Iodoacetamide-PEG3-azide Structure
Iodoacetamide-PEG3-azide structure
Common Name Iodoacetamide-PEG3-azide
CAS Number 1594986-04-5 Molecular Weight 386.19
Density N/A Boiling Point N/A
Molecular Formula C10H19IN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Iodoacetamide-PEG3-azide


Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Iodoacetamide-PEG3-azide

 Iodoacetamide-PEG3-azide Biological Activity

Description Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H19IN4O4
Molecular Weight 386.19