Huwentoxin XVI TFA
Modify Date: 2025-08-27 16:07:13
Huwentoxin XVI TFA structure
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Common Name | Huwentoxin XVI TFA | ||
|---|---|---|---|---|
| CAS Number | 1600543-88-1 | Molecular Weight | 4437.13 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C196H292N50O56S6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Huwentoxin XVI TFAHuwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels[1]. |
| Name | Huwentoxin XVI |
|---|
| Description | Huwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels[1]. |
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| Related Catalog | |
| Target |
IC50: ~60 nM (N-type calcium channel)[1] |
| References |
| Molecular Formula | C196H292N50O56S6 |
|---|---|
| Molecular Weight | 4437.13 |
| InChIKey | JEUFUDFTZMBKGH-UHFFFAOYSA-N |
| SMILES | CCC(C)C1NC(=O)CNC(=O)C(Cc2c[nH]cn2)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C2CCCN2C(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C2CSSCC3NC(=O)C4CCCN4C(=O)C(C(C)C)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(C(C)CC)NC(=O)C(N)CSSCC(NC(=O)C(CSSCC(C(=O)NC(Cc4ccc(O)cc4)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(Cc4c[nH]c5ccccc45)NC1=O)NC(=O)C(CCCNC(=N)N)NC(=O)C1CCCN1C(=O)C(CC(=O)O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC3=O)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)N2 |