Aeruginosin 865
Modify Date: 2025-08-25 11:49:48
Aeruginosin 865 structure
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Common Name | Aeruginosin 865 | ||
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| CAS Number | 1611990-01-2 | Molecular Weight | 864.98 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C41H64N6O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aeruginosin 865Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp. Lukešová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect[1] |
| Name | Aeruginosin 865 |
|---|
| Description | Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp. Lukešová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect[1] |
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| Related Catalog | |
| In Vitro | Aeruginosin 865 (pretreatment with 0.1-100 μg/mL) shows significant inhibition of IL-8 (EC50=3.5 μg/mL) and ICAM-1 (EC50=50.0 μg/mL) in hTNF-α-stimulated HLMVECs in a concentration-dependent manner. Aeruginosin 865 does not affect cell viability, even at much higher concentration in HeLa, HepG2 cells[1]. Aeruginosin 865 (100-200 μM) shows high-dose cytotoxicity in Mouse fibrosarcoma cells and with no cytotoxic effect in NIH/3T3 cells[2]. . |
| References |
| Molecular Formula | C41H64N6O14 |
|---|---|
| Molecular Weight | 864.98 |
| InChIKey | GYBRMQYCKSSXID-RIDHWVDWSA-N |
| SMILES | CCCCCC(=O)OC1CC2CC(C(=O)NCCCCN=C(N)N)N(C(=O)C(CC(C)C)NC(=O)C(O)Cc3ccc(O)cc3)C2CC1OC1OC(C(=O)O)C(O)C(O)C1O |