Esomeprazole sodium

Modify Date: 2024-01-02 17:29:58

Esomeprazole sodium Structure
Esomeprazole sodium structure
 Common Name Esomeprazole sodium
CAS Number 161796-78-7 Molecular Weight 367.398
Density N/A Boiling Point 600ºC at 760 mmHg
Molecular Formula C17H18N3NaO3S Melting Point N/A
MSDS N/A Flash Point 316.7ºC

 Use of Esomeprazole sodium


Esomeprazole sodium is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis. Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.

 Names

Name Esomeprazole sodium
Synonym More Synonyms

 Esomeprazole sodium Biological Activity

Description Esomeprazole sodium is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis. Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.
Related Catalog
References

[1]. Sandstr?m M, Davidson G, Tolia V et al. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age. Clin Ther. 2012 Aug;34(8):1828-38.

[2]. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.

[3]. Thomas C Kupiec, Vasileios Aloumanis, Michel Ben, et al. Physical and Chemical Stability of Esomeprazole Sodium Solutions. Ann Pharmacother. September 2008 ,42 ( 9 ):1247-1251.

[4]. Esomeprazole

 Chemical & Physical Properties

Boiling Point 600ºC at 760 mmHg
Molecular Formula C17H18N3NaO3S
Molecular Weight 367.398
Flash Point 316.7ºC
Exact Mass 367.096649
PSA 85.45000
LogP 3.55120
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

esomeprazole sodium
Esomeprazole (sodium)
Natrium-5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-id
1H-Benzimidazole, 5-methoxy-2-[(S)-[(1S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
Sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide
sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide
(S)-OMeprazole sodiuM
odiuM (R)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide
1H-benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
5-méthoxy-2-{(S)-[(4-méthoxy-3,5-diméthylpyridin-2-yl)méthyl]sulfinyl}benzimidazol-1-ide de sodium
SodiuM (S)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide
1H-BENZIMIDAZOLE,5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-,SODIUM SALT
Esomeprazoleandsalts
Esomeprazole
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Esomeprazole sodium suppliers

Price: ￥413.4/5mg

Reference only. check more Esomeprazole sodium price

Related Compounds: More...
Esomeprazole-d6 sodium
922731-04-2
Esomeprazole magnesium hydrate
668985-31-7
Esomeprazole
161973-10-0
Esomeprazole magnesium
217087-09-7
acediasulfone sodium
127-60-6
ibuprofen sodium salt
31121-93-4
Aminonaphtylsulphonate sodium
30605-57-3
Propylparaben sodium
35285-69-9
Methylparaben Sodium Salt
5026-62-0
7-methyl-5H-spiro[benzo[c]pyrano[3,2-g]chromene-9,1'-cyclohexane]-5,11(10H)-dione
921135-28-6
2,2,4-Trimethyl-1-{[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]acetyl}-1,2-dihydroquinoline
925019-32-5
7-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-2-methyl-3-phenyl-4H-chromen-4-one
921084-42-6
(2Z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydro-1-benzofuran-6-yl 4-chlorobenzenesulfonate
929372-76-9
8-(3-((4-methoxyphenyl)amino)propyl)-1,7-dimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
923686-36-6
N-[(3-Phenyl-2,1-benzisoxazol-5-yl)carbonyl]-L-valine
957039-66-6
Methyl 3-(4-hydroxy-3-nitrophenyl)propionate
179103-68-5
ethyl 3-[1-(4,6-dimethylpyrimidin-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanoate
1006580-87-5
(2Z)-7-{[benzyl(methyl)amino]methyl}-2-(2,5-dimethoxybenzylidene)-6-hydroxy-1-benzofuran-3(2H)-one
929456-91-7
5-(Allylthio)-2-(2-methoxyphenyl)[1,2,4]triazolo[1,5-c]quinazoline
925182-33-8
Chemsrc provides Esomeprazole sodium(CAS#:161796-78-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Esomeprazole sodium are included as well.>> amp version: Esomeprazole sodium

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved