Thrombin inhibitor 6 structure
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Common Name | Thrombin inhibitor 6 | ||
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CAS Number | 1628224-94-1 | Molecular Weight | 390.89 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H19ClN4O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Thrombin inhibitor 6Thrombin inhibitor 6 is a potent thrombin inhibitor (IC50: 1 nM). Thrombin inhibitor 6 has the function as an anticoagulant[1]. |
Name | Thrombin inhibitor 6 |
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Description | Thrombin inhibitor 6 is a potent thrombin inhibitor (IC50: 1 nM). Thrombin inhibitor 6 has the function as an anticoagulant[1]. |
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Related Catalog | |
In Vitro | Thrombin inhibitor 6 (compound 73) 在与 CD-1 小鼠和人微粒体孵育时是稳定的 (Clint (小鼠) = 60 μL/min/mg;Clint (人) = 17 μL/min/mg)[1]. |
In Vivo | Thrombin inhibitor 6 (compound 73) (9 mg/kg,静脉注射) 可延长 CD-1 小鼠的尾部出血时间[1]。 Thrombin inhibitor 6 (compound 73) (5 mg/kg,口服) 在雄性 CD-1 小鼠中的 F(%) 为 22.8%,AUC 为 713.3 h.ng/mL,Cmax 为 127 ng/mL[1]。 Animal Model: CD-1 mice[1] Dosage: 9 mg/kg Administration: Intravenous injection (i.v.) Result: The mice bled for 25 min following transection. Led to 1.5-fold increase of liberated whole blood cells. |
References |
Molecular Formula | C18H19ClN4O2S |
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Molecular Weight | 390.89 |