Tubulin inhibitor 6

Modify Date: 2024-01-12 00:24:19

Tubulin inhibitor 6 Structure
Tubulin inhibitor 6 structure
Common Name Tubulin inhibitor 6
CAS Number 105925-39-1 Molecular Weight 367.85
Density N/A Boiling Point N/A
Molecular Formula C20H14ClNO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tubulin inhibitor 6


Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].

 Names

Name Tubulin inhibitor 6
Synonym More Synonyms

 Tubulin inhibitor 6 Biological Activity

Description Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].
Related Catalog
Target

IC50: 0.87 μM (tubulin polymerization)[1]

In Vitro Tubulin inhibitor 6 displays submicromolar antiproliferative activity[1].
References

[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

 Chemical & Physical Properties

Molecular Formula C20H14ClNO2S
Molecular Weight 367.85

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD01245092