HUMAN BETACELLULIN structure
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Common Name | HUMAN BETACELLULIN | ||
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CAS Number | 163150-12-7 | Molecular Weight | N/A | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | N/A | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Name | HUMAN BETACELLULIN |
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Appearance of Characters | lyophilized powder |
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Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice.
Exp. Mol. Med. 46 , e98, (2014) Type 1 diabetes is an autoimmune disease caused by permanent destruction of insulin-producing pancreatic β cells and requires lifelong exogenous insulin therapy. Recently, islet transplantation has be... |
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Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta.
Oncogene 12 , 345, (1996) Betacellulin is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the erbB gene family (erbB-1/e... |
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Immunohistochemical localization of betacellulin, a new member of the EGF family, in normal human pancreas and islet tumor cells.
Endocrine J. 46 , 755-764, (1999) Betacellulin (BTC) purified from mouse beta cell tumor (betaTC-3) is a new member of the epidermal growth factor (EGF) family which can bind receptor tyrosine kinase, EGF receptor (erbB1) and erbB4. I... |