1,4-Butane sultone

Modify Date: 2024-01-02 08:07:40

1,4-Butane sultone Structure
1,4-Butane sultone structure
Common Name 1,4-Butane sultone
CAS Number 1633-83-6 Molecular Weight 136.169
Density 1.3±0.1 g/cm3 Boiling Point 299.9±9.0 °C at 760 mmHg
Molecular Formula C4H8O3S Melting Point 12.5-15ºC
MSDS Chinese USA Flash Point 135.2±18.7 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name 1,4-Butane Sultone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 299.9±9.0 °C at 760 mmHg
Melting Point 12.5-15ºC
Molecular Formula C4H8O3S
Molecular Weight 136.169
Flash Point 135.2±18.7 °C
Exact Mass 136.019409
PSA 51.75000
LogP -0.13
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.471
Water Solubility 54 g/L (20 ºC) decomposes

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP4300000
CHEMICAL NAME :
1,2-Oxathiane, 2,2-dioxide
CAS REGISTRY NUMBER :
1633-83-6
BEILSTEIN REFERENCE NO. :
0110588
LAST UPDATED :
199701
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C4-H8-O3-S
MOLECULAR WEIGHT :
136.18
WISWESSER LINE NOTATION :
T6OSWTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 mg/kg/1Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Reproductive - Tumorigenic effects - ovarian tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2280 mg/kg/76W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1680 mg/kg/42W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
5 mg/L
REFERENCE :
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 19,642,1977

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302-H351
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R22;R68
Safety Phrases S36/37-S45
RIDADR UN 2810
WGK Germany 3
RTECS RP4300000
Packaging Group III
Hazard Class 6.1(b)
HS Code 29349990

 Synthetic Route

 Customs

HS Code 2934991000
Summary 2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

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For the development of renewable bioproducts able to solubilize organic persistent pollutant such as benzo[a]pyrene (BaP), modified potato starch was synthesized by alkylation. The addition of alkyl c...

Determination of the substituent distribution in O-sulfonylbutyl-(1-->4)-glucans.

Carbohydr. Res. 327(3) , 275-85, (2000)

A method has been developed to determine the distribution of substituents in the glucose units of sulfonylbutylethers of cyclomaltoheptaose (beta-cyclodextrin). This method involves hydrolysis of the ...

Formation of unexpected substitution patterns in sulfonylbutylation of cyclomaltoheptaose promoted by host-guest interaction.

Carbohydr. Res. 327(3) , 269-74, (2000)

The distribution of substituents in sulfonylbutylethers of cyclomaltoheptaose (beta-cyclodextrin) formed in aqueous medium has been determined by gas chromatography after hydrolysis and formation of t...

 Synonyms

1,2-Oxathiane, 2,2-dioxide
oxathiane 2,2-dioxide
1,4-Butane sultone
EINECS 216-647-9
MFCD00006584
1,2-Oxathiane 2,2-dioxide
1,4-Butanesultone
1.4-Butane Sultone
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