p38 MAP Kinase Inhibitor IV
Modify Date: 2024-01-04 11:31:06
p38 MAP Kinase Inhibitor IV structure
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Common Name | p38 MAP Kinase Inhibitor IV | ||
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| CAS Number | 1638-41-1 | Molecular Weight | 456.94100 | |
| Density | 1.854 g/cm3 | Boiling Point | 590ºC at 760 mmHg | |
| Molecular Formula | C12H4Cl6O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 310.6ºC | |
Use of p38 MAP Kinase Inhibitor IVp38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively[1]. |
| Name | phenol,2,2'-sulfonylbis[3,4,6-trichloro] |
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| Synonym | More Synonyms |
| Description | p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively[1]. |
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| Related Catalog | |
| Target |
p38α:0.13 μM (IC50) p38β:0.55 μM (IC50) p38δ:8.63 μM (IC50) p38χ:5.47 μM (IC50) |
| In Vitro | p38 MAP Kinase Inhibitor IV (MT4) shows IC50 values of 0.13, 0.55, 5.47, and 8.63μM for p38α, β, χ, andδ, respectively. p38 MAP Kinase Inhibitor IV has the suppressive action on the release of TNF-alpha and IL-1beta in PBMC with IC50 values of 22 and 44 nM, respectively[1]. |
| References |
| Density | 1.854 g/cm3 |
|---|---|
| Boiling Point | 590ºC at 760 mmHg |
| Molecular Formula | C12H4Cl6O4S |
| Molecular Weight | 456.94100 |
| Flash Point | 310.6ºC |
| Exact Mass | 453.79600 |
| PSA | 82.98000 |
| LogP | 6.93180 |
| RIDADR | NONH for all modes of transport |
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| HS Code | 2908999090 |
| HS Code | 2908999090 |
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| Summary | 2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
| p38 MAP Kinase Inhibitor IV |
| 2,2'-Sulfonylbis(3,4,6-trichlorophenol) |
| Bis-(3,5,6-Trichlor-2-hydroxyphenyl)-sulfon |
| Bis-(3,5,6-trichlor-2-hydroxyphenyl)sulfid |