m-PEG6-amino-Mal

Modify Date: 2024-01-02 18:38:00

m-PEG6-amino-Mal Structure
m-PEG6-amino-Mal structure
Common Name m-PEG6-amino-Mal
CAS Number 1644231-07-1 Molecular Weight 446.492
Density 1.2±0.1 g/cm3 Boiling Point 604.5±55.0 °C at 760 mmHg
Molecular Formula C20H34N2O9 Melting Point N/A
MSDS N/A Flash Point 319.4±31.5 °C

 Use of m-PEG6-amino-Mal


m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name MPEG6-Mal
Synonym More Synonyms

 m-PEG6-amino-Mal Biological Activity

Description m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 604.5±55.0 °C at 760 mmHg
Molecular Formula C20H34N2O9
Molecular Weight 446.492
Flash Point 319.4±31.5 °C
Exact Mass 446.226440
LogP -2.78
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.493

 Synonyms

1H-Pyrrole-1-propanamide, N-3,6,9,12,15,18-hexaoxanonadec-1-yl-2,5-dihydro-2,5-dioxo-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17-hexaoxanonadecan-19-yl)propanamide
MFCD27977520
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