PU-141
Modify Date: 2024-04-05 10:41:35
PU-141 structure
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Common Name | PU-141 | ||
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| CAS Number | 168334-34-7 | Molecular Weight | 310.294 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H9F3N2OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PU-141PU-141 is a potent, selective CBP/p300 inhibitor that inhibits SK-N-SH cell growth with GI50 of 0.48 uM; blocks growth of SK-N-SH neuroblastoma xenografts in mice, also reduces histone lysine acetylation in vivo at concentrations that block neoplastic xenograft growth. |
| Name | PU-141 |
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| Description | PU-141 is a potent, selective CBP/p300 inhibitor that inhibits SK-N-SH cell growth with GI50 of 0.48 uM; blocks growth of SK-N-SH neuroblastoma xenografts in mice, also reduces histone lysine acetylation in vivo at concentrations that block neoplastic xenograft growth. |
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| References | References 1. Gajer JM, et al. Oncogenesis. 2015 Feb 9;4:e137. 2. Furdas SD, et al. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89. View Related Products by Target Histone Acetyltransferase (HAT) |
| Molecular Formula | C14H9F3N2OS |
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| Molecular Weight | 310.294 |
| Hazard Codes | Xi |
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