Eleutheroside B1

Modify Date: 2025-08-21 18:06:34

Eleutheroside B1 Structure
Eleutheroside B1 structure
Common Name Eleutheroside B1
CAS Number 16845-16-2 Molecular Weight 384.33500
Density N/A Boiling Point N/A
Molecular Formula C17H20O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Eleutheroside B1


Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].

 Names

Name eleutheroside B1

 Eleutheroside B1 Biological Activity

Description Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].
Related Catalog
In Vitro Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1]. RT-PCR[1] Cell Line: Virus-infected A549 cells Concentration: 100 µg/ml Incubation Time: 24 hours Result: The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.
References

[1]. Yan W, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.Int J Mol Med. 2018 Nov;42(5):2776-2792.

 Chemical & Physical Properties

Molecular Formula C17H20O10
Molecular Weight 384.33500
Exact Mass 384.10600
PSA 148.05000
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