Eleutheroside B1
Modify Date: 2024-01-02 19:52:14
Eleutheroside B1 structure
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Common Name | Eleutheroside B1 | ||
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| CAS Number | 16845-16-2 | Molecular Weight | 384.33500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H20O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Eleutheroside B1Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1]. |
| Name | eleutheroside B1 |
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| Description | Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1]. |
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| Related Catalog | |
| In Vitro | Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1]. RT-PCR[1] Cell Line: Virus-infected A549 cells Concentration: 100 µg/ml Incubation Time: 24 hours Result: The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. |
| References |
| Molecular Formula | C17H20O10 |
|---|---|
| Molecular Weight | 384.33500 |
| Exact Mass | 384.10600 |
| PSA | 148.05000 |