AZ PFKFB3 67

Modify Date: 2025-11-28 19:24:42

AZ PFKFB3 67 Structure
AZ PFKFB3 67 structure
Common Name AZ PFKFB3 67
CAS Number 1704741-11-6 Molecular Weight 455.51
Density N/A Boiling Point N/A
Molecular Formula C26H25N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AZ PFKFB3 67


AZ-PFKFB3-67 is potent and selective PFKFB3 kinase inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively[1].

 Names

Name AZ-PFKFB3-67

 AZ PFKFB3 67 Biological Activity

Description AZ-PFKFB3-67 is potent and selective PFKFB3 kinase inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively[1].
Related Catalog
References

[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015;58(8):3611-3625.

 Chemical & Physical Properties

Molecular Formula C26H25N5O3
Molecular Weight 455.51
InChIKey NDIKFKQBWGMLCA-DEOSSOPVSA-N
SMILES Cc1noc(C)c1Cn1cc(C#N)c2cc(Oc3ccc(NC(=O)C4CCCN4)cc3)ccc21
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