AZ PFKFB3 26

Modify Date: 2024-01-08 12:09:36

AZ PFKFB3 26 Structure
AZ PFKFB3 26 structure
Common Name AZ PFKFB3 26
CAS Number 1704740-52-2 Molecular Weight 402.49
Density N/A Boiling Point N/A
Molecular Formula C24H26N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AZ PFKFB3 26


AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1].

 Names

Name AZ PFKFB3 26

 AZ PFKFB3 26 Biological Activity

Description AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1].
Related Catalog
Target

IC50: 23 nM (PFKFB3), 2.06 μM (PFKFB1), 0.384 μM (PFKFB2)[1]

References

[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015 Apr 23;58(8):3611-25.

 Chemical & Physical Properties

Molecular Formula C24H26N4O2
Molecular Weight 402.49
Storage condition 2-8℃
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