6-nitro-2-(4-nitrophenyl)-1H-benzimidazole

Modify Date: 2025-08-26 19:08:32

6-nitro-2-(4-nitrophenyl)-1H-benzimidazole structure	Common Name	6-nitro-2-(4-nitrophenyl)-1H-benzimidazole
	CAS Number	1772-39-0	Molecular Weight	284.22700
	Density	1.544g/cm3	Boiling Point	565.2ºC at 760mmHg
	Molecular Formula	C₁₃H₈N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	295.6ºC

Use of 6-nitro-2-(4-nitrophenyl)-1H-benzimidazole

MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively[1].

Name	6-nitro-2-(4-nitrophenyl)-1H-benzimidazole
Synonym	More Synonyms

Description	MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-2:4.2 ± 0.2 μM (IC50) MMP13:12 ± 7 μM (IC50) MMP-9:23.3 ± 10. μM (IC50) MMP-8:25 ± 10 μM (IC50)
References	[1]. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.

Density	1.544g/cm3
Boiling Point	565.2ºC at 760mmHg
Molecular Formula	C₁₃H₈N₄O₄
Molecular Weight	284.22700
Flash Point	295.6ºC
Exact Mass	284.05500
PSA	120.32000
LogP	4.09270
Vapour Pressure	8.54E-13mmHg at 25°C
Index of Refraction	1.74

HS Code	2933990090

Precursor 0
DownStream 2
CAS#:71002-88-5 4-(5-NITRO-1H-B... CAS#:7621-86-5 2-(4-aminopheny...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MMP2-IN-2
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Nsc-657186
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.