PD-159020
Modify Date: 2025-09-18 17:59:15
PD-159020 structure
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Common Name | PD-159020 | ||
|---|---|---|---|---|
| CAS Number | 177904-00-6 | Molecular Weight | 551.543 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 758.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C32H25NO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 412.4±32.9 °C | |
Use of PD-159020PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively. |
| Name | PD-159020 |
|---|---|
| Synonym | More Synonyms |
| Description | PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively. |
|---|---|
| Related Catalog | |
| Target |
IC50: 30 nM (hETA), 50 nM (hETB)[1] |
| In Vitro | PD-159020 demonstrates excellent inhibition of arachidonic acid release, AAR-B, with an IC50 of 0.23 μM. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 758.3±60.0 °C at 760 mmHg |
| Molecular Formula | C32H25NO8 |
| Molecular Weight | 551.543 |
| Flash Point | 412.4±32.9 °C |
| Exact Mass | 551.158020 |
| LogP | 5.92 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.670 |
| InChIKey | BOQQYCYLUTYLGS-UHFFFAOYSA-N |
| SMILES | COc1cc2c(-c3ccc4c(c3)OCO4)c(C(=O)O)n(Cc3ccc4c(c3)OCO4)c2cc1OCc1ccccc1 |
| Storage condition | 2-8℃ |
| 1H-Indole-2-carboxylic acid, 3-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-5-methoxy-6-(phenylmethoxy)- |
| 3-(1,3-Benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-6-(benzyloxy)-5-methoxy-1H-indole-2-carboxylic acid |