Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

Modify Date: 2025-08-27 11:05:26

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc Structure
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc structure
Common Name Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
CAS Number 1799711-31-1 Molecular Weight 634.67
Density N/A Boiling Point N/A
Molecular Formula C30H42N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc


Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).

 Names

Name Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

 Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc Biological Activity

Description Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).
Related Catalog
Target

Cereblon

References

[1]. Shaomeng Wang, et al. Bet protein degraders. WO2017180417A1.

 Chemical & Physical Properties

Molecular Formula C30H42N4O11
Molecular Weight 634.67
InChIKey GUERDSNOMPTZOW-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NCCCOCCOCCOCCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
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