Pyrene-PEG5-propargyl

Modify Date: 2024-01-09 18:47:44

Pyrene-PEG5-propargyl structure	Common Name	Pyrene-PEG5-propargyl
	CAS Number	1817735-33-3	Molecular Weight	503.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₃NO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pyrene-PEG5-propargyl

Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Pyrene-PEG5-propargyl

Description	Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₀H₃₃NO₆
Molecular Weight	503.59