Pyrene-PEG5-alcohol

Modify Date: 2024-01-09 18:47:34

Pyrene-PEG5-alcohol Structure
Pyrene-PEG5-alcohol structure
Common Name Pyrene-PEG5-alcohol
CAS Number 1817735-44-6 Molecular Weight 465.54
Density N/A Boiling Point N/A
Molecular Formula C27H31NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pyrene-PEG5-alcohol


Pyrene-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Pyrene-PEG5-alcohol

 Pyrene-PEG5-alcohol Biological Activity

Description Pyrene-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H31NO6
Molecular Weight 465.54
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