DSPE-PEG5-propargyl

Modify Date: 2024-01-17 18:42:03

DSPE-PEG5-propargyl Structure
DSPE-PEG5-propargyl structure
Common Name DSPE-PEG5-propargyl
CAS Number 2112737-93-4 Molecular Weight 1034.39
Density N/A Boiling Point N/A
Molecular Formula C55H104NO14P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSPE-PEG5-propargyl


DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DSPE-PEG5-propargyl

 DSPE-PEG5-propargyl Biological Activity

Description DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C55H104NO14P
Molecular Weight 1034.39