fluorophenothiazine dihydrochloride

Modify Date: 2023-10-18 19:17:43

fluorophenothiazine dihydrochloride Structure
fluorophenothiazine dihydrochloride structure
Common Name fluorophenothiazine dihydrochloride
CAS Number 1827-91-4 Molecular Weight 518.03500
Density 1.256g/cm3 Boiling Point 600.4ºC at 760 mmHg
Molecular Formula C24H31ClF3N3O2S Melting Point N/A
MSDS N/A Flash Point 316.9ºC

 Names

Name fluorophenothiazine dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.256g/cm3
Boiling Point 600.4ºC at 760 mmHg
Molecular Formula C24H31ClF3N3O2S
Molecular Weight 518.03500
Flash Point 316.9ºC
Exact Mass 517.17800
PSA 64.48000
LogP 5.06750
Vapour Pressure 2.9E-15mmHg at 25°C
Index of Refraction 1.567

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM5425000
CHEMICAL NAME :
Ethanol, 2-(2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)pro pyl)-1-piperazinyl)et hoxy)-, dihydrochloride
CAS REGISTRY NUMBER :
1827-91-4
LAST UPDATED :
199506
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C24-H30-F3-N3-O2-S.2Cl-H
MOLECULAR WEIGHT :
554.55
WISWESSER LINE NOTATION :
T C666 BN ISJ EXFFF B3- AT6N DNTJ D2O2Q &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
588 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
199 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962

 Synonyms

Piclopastine