Brevifolincarboxylic acid

Modify Date: 2024-01-02 10:20:49

Brevifolincarboxylic acid structure	Common Name	Brevifolincarboxylic acid
	CAS Number	18490-95-4	Molecular Weight	292.198
	Density	2.0±0.1 g/cm3	Boiling Point	758.5±60.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₈O₈	Melting Point	250 °C
	MSDS	N/A	Flash Point	296.2±26.4 °C

Use of Brevifolincarboxylic acid

Brevifolincarboxylic acid is extracted from Polygonum capitatum[1], has inhibitory effect on the aryl hydrocarbon receptor (AhR)[2]. Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 323.46 μM[3].

Name	brevifolin carboxylic acid
Synonym	More Synonyms

Description	Brevifolincarboxylic acid is extracted from Polygonum capitatum[1], has inhibitory effect on the aryl hydrocarbon receptor (AhR)[2]. Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 323.46 μM[3].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Aryl Hydrocarbon Receptor Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	IC50: 323.46 μM (α-glucosidase) (Brevifolincarboxylic acid)[3]
References	[1]. Chen X, et al. Simultaneous isolation and purification of gallic acid and brevifolincarboxylic acid from Polygonum capitatum by high-speed counter-current chromatography. Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1957-60. [2]. Amakura Y, et al. Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biol Pharm Bull. 2003 Dec; 26(12):1754-60. [3]. Liu M, et al. Separation of α-glucosidase inhibitors from Potentilla kleiniana Wight et Arn using solvent and flow-rate gradient high-speed counter-current chromatography target-guided by ultrafiltration HPLC-MS screening. Phytochem Anal. 2019 May 6.

Density	2.0±0.1 g/cm3
Boiling Point	758.5±60.0 °C at 760 mmHg
Melting Point	250 °C
Molecular Formula	C₁₃H₈O₈
Molecular Weight	292.198
Flash Point	296.2±26.4 °C
Exact Mass	292.021912
PSA	145.27000
LogP	0.99
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.802