AMPK activator 8
Modify Date: 2024-01-23 19:17:59
AMPK activator 8 structure
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Common Name | AMPK activator 8 | ||
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| CAS Number | 1852451-96-7 | Molecular Weight | 480.90 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H21ClN2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AMPK activator 8AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1]. |
| Name | AMPK activator 8 |
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| Description | AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1]. |
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| Related Catalog | |
| In Vitro | AMPK activator 8 (compound 2) acts on rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ and rAMPK α2β2γ3 with the EC50 value of 11 nM, 27 nM, 4 nM, 2 nM and 4 nM, respectively[1]. AMPK activator 8 (compound 2) affects cell viability[1]. Cell Viability Assay[1] Cell Line: HepG2, C2C12 myoblasts Concentration: 0.01-1000 μM Incubation Time: 1 hour Result: Resulted in HepG2 and C2C12 myoblasts with the EC50 value of 255 nM and 230 nM, respectively. |
| References |
[1]. Mathilde Muzerelle, et al. Novel activators of amp-activated protein kinases.WO2016001224A1 |
| Molecular Formula | C25H21ClN2O6 |
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| Molecular Weight | 480.90 |