BMS 193885
Modify Date: 2024-01-06 06:21:22
BMS 193885 structure
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Common Name | BMS 193885 | ||
|---|---|---|---|---|
| CAS Number | 186185-03-5 | Molecular Weight | 590.71000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C33H42N4O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of BMS 193885BMS-193885 is a potent, selective, competitive, and brain penetrant neuropeptide Y1 receptor antagonist with a Ki of 3.3 nM, and has an IC50 of 5.9 nM for hY1, which displays > 100, > 160, > 160 and > 160-fold selectivity over α1, hY2, hY4 and hY5 receptors, respectively [1] [2]. |
| Name | dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | BMS-193885 is a potent, selective, competitive, and brain penetrant neuropeptide Y1 receptor antagonist with a Ki of 3.3 nM, and has an IC50 of 5.9 nM for hY1, which displays > 100, > 160, > 160 and > 160-fold selectivity over α1, hY2, hY4 and hY5 receptors, respectively [1] [2]. |
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| Related Catalog | |
| Target |
Ki: 3.3 nM (Neuropeptide Y1 receptor)[1] IC50: 5.9 nM (hY1)[1] |
| References |
| Molecular Formula | C33H42N4O6 |
|---|---|
| Molecular Weight | 590.71000 |
| Exact Mass | 590.31000 |
| PSA | 121.72000 |
| LogP | 5.21130 |
| MFCD16878998 |