Bimosiamose

Modify Date: 2024-01-11 16:35:07

Bimosiamose Structure
Bimosiamose structure
Common Name Bimosiamose
CAS Number 187269-40-5 Molecular Weight 862.911
Density 1.4±0.1 g/cm3 Boiling Point 1051.0±65.0 °C at 760 mmHg
Molecular Formula C46H54O16 Melting Point N/A
MSDS N/A Flash Point 309.7±27.8 °C

 Use of Bimosiamose


Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.

 Names

Name bimosiamose
Synonym More Synonyms

 Bimosiamose Biological Activity

Description Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.
Related Catalog
Target

IC50: 88 μM (E-selectin), 20 μM (P-selectin), 86 μM (L-selectin)[1]

In Vitro Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease[1].
In Vivo Bimosiamose (25 mg/kg, i.v.) significantly improves the survival in rats subjected to severe hepatic ischemia and reperfusion. Bimosiamose also causes lower ALT enzyme levels and decreases neutrophil infiltration[1].
References

[1]. Palma-Vargas JM, et al. Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion. J Am Coll Surg. 1997 Oct;185(4):365-72.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1051.0±65.0 °C at 760 mmHg
Molecular Formula C46H54O16
Molecular Weight 862.911
Flash Point 309.7±27.8 °C
Exact Mass 862.341187
LogP 3.04
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.649

 Safety Information

Hazard Codes Xn

 Synonyms

bimosiamose
[1,1'-Biphenyl]-3-acetic acid, 3',3''-(1,6-hexanediyl)bis[6'-(α-D-mannopyranosyloxy)-
97B5KCW80W
2,2'-{1,6-Hexanediylbis[6'-(α-D-mannopyranosyloxy)-3',3-biphenyldiyl]}diacetic acid
8074
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Bimosiamose
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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