PCSK9 modulator 10
Modify Date: 2024-09-08 12:21:01
PCSK9 modulator 10 structure
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Common Name | PCSK9 modulator 10 | ||
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| CAS Number | 1874254-18-8 | Molecular Weight | 365.659 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H6ClF6NO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PCSK9 modulator 10PCSK9 modulator 10 is a highly potent, orally active PCSK9 modulator that inhibits PCSK9 production in HepG2 cells with IC50 of 0.036 nM; significantly reduces LDL-c levels by 46% and 57% at 0.01 and 0.04 mg/kg in vivo without deaths or abnormal general signs. |
| Name | PCSK9 modulator 10 |
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| Description | PCSK9 modulator 10 is a highly potent, orally active PCSK9 modulator that inhibits PCSK9 production in HepG2 cells with IC50 of 0.036 nM; significantly reduces LDL-c levels by 46% and 57% at 0.01 and 0.04 mg/kg in vivo without deaths or abnormal general signs. |
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| References | References 1. Daniel Pettersen, et al. Small molecule modulators of PCSK9-a literature and patent overview. Bioorg Med Chem Lett. 2018 Feb 26. pii: S0960-894X(18)30151-3. View Related Products by Target PCSK9 |
| Molecular Formula | C15H6ClF6NO |
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| Molecular Weight | 365.659 |