I-PEG5-OH

Modify Date: 2024-01-16 16:39:25

I-PEG5-OH Structure
I-PEG5-OH structure
Common Name I-PEG5-OH
CAS Number 1883516-31-1 Molecular Weight 348.18
Density N/A Boiling Point N/A
Molecular Formula C10H21IO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of I-PEG5-OH


I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name I-PEG5-OH

 I-PEG5-OH Biological Activity

Description I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H21IO5
Molecular Weight 348.18