THP-PEG5-OH

Modify Date: 2025-08-25 23:41:07

THP-PEG5-OH Structure
THP-PEG5-OH structure
Common Name THP-PEG5-OH
CAS Number 146395-14-4 Molecular Weight 322.395
Density 1.1±0.1 g/cm3 Boiling Point 432.5±45.0 °C at 760 mmHg
Molecular Formula C15H30O7 Melting Point N/A
MSDS N/A Flash Point 215.4±28.7 °C

 Use of THP-PEG5-OH


THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name THP-PEG6
Synonym More Synonyms

 THP-PEG5-OH Biological Activity

Description THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 432.5±45.0 °C at 760 mmHg
Molecular Formula C15H30O7
Molecular Weight 322.395
Flash Point 215.4±28.7 °C
Exact Mass 322.199158
LogP -1.82
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.469

 Synonyms

3,6,9,12-Tetraoxatetradecan-1-ol, 14-[(tetrahydro-2H-pyran-2-yl)oxy]-
14-(Tetrahydro-2H-pyran-2-yloxy)-3,6,9,12-tetraoxatetradecan-1-ol
MFCD26793753
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